Reflective Practive

Primary Biliary Cirrhosis

The tests available to support the diagnosis of Primary Biliary Cirrhosis are:

EliA M2 (14-5649-01)

EliA M2 provides high sensitivity and specificity, potentially helping to reduce the time to diagnosis1 Performance data of EliA M2 and M2 ELISAs from two other suppliers in 100 sera from PBC patients and 210 sera from disease controls1

Cut-off/measuring range

 
Negative Equivocal Positive Measuring range
EliA M2 <4 GPL-U/ml 4-6 GPL-U/ml >6 GPL-U/ml 0.5-≥220 U/ml

Coating

  • Native pyruvate dehydrogenase complex from mitochondria and recombinant M2-antigen

Dilution

  • 1:100

Sample material

  • Serum, plasma (EDTA, citrate, heparin)

Cut-off/measuring range, coating, dilution and sample material have been taken from respective Phadia 250 DFUs. The data is intended as a guide and should be treated accordingly. If you have any questions or uncertainty please contact your local service team or Laboratory Sales Representative.

References
  1. Thermo Fisher Scientific. Internal study.

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