Autoimmune Thyroid Disease
The tests available to support the diagnosis of ATD are:
EliA™ TPO (14-5641-01) / EliA TG (14-5642-01)
EliA TPO and EliA TG have excellent sensitivity and specificity - helping to rapidly provide clinical insight in patients with autoimmune thyroid disease1
Performance of EliA TPO and EliA TG in 400 samples (100 Hashimoto's and Graves' disease; controls 50 non-AI Thyroiditis, 25 CTD, 10 IBD, 10 PBC, 20 HIV, 20 HCV, 20 HBV, 20 other infectious and 25 cancer samples); internal study (data on file).
*Positive predictive value
Cut-off/measuring range
| Negative | Equivocal | Positive | Measuring range | |
|---|---|---|---|---|
| EliA TG | <40 GPL-U/ml | 40-60 GPL-U/ml | >60 GPL-U/ml | 2-≥4794 U/ml |
| EliA TPO | <25 U/ml | 25-35 U/ml | >35 U/ml | 4-≥1542 U/ml |
Coating
- EliA TPO - human recombinant TPO antigen
- EliA TG - human thyroglobulin antigen
Dilution
- EliA TPO - 1:200
- EliA TG - 1:100
Sample material
- Serum, plasma (EDTA, citrate, heparin)
Cut-off/measuring range, coating, dilution and sample material have been taken from respective Phadia 250 DFUs. The data is intended as a guide and should be treated accordingly. If you have any questions or uncertainty please contact your local service team or Laboratory Sales Representative.
- Thermo Fisher Scientific. Internal Study.
